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POLIOVIRUS — COMPLETE MICROBIOLOGY + CLINICAL + PUBLIC-HEALTH REVIEW
1. Basic classification Characteristic Poliovirus Family Picornaviridae Genus Enterovirus Species Enterovirus C Genome ssRNA, positive sense Envelope Absent Capsid Icosahedral Genome size ~7.4 kb Replication Cytoplasm Replication strategy Positive-sense RNA directly functions as mRNA Major receptor CD155/PVR — poliovirus receptor Serotypes PV1, PV2, PV3 Natural host Humans Major transmission Feco-oral Main site of multiplication Oropharynx + intestine Major target in paralyti
Dr Harish M Nair
Aug 1218 min read
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